Taste Receptor Genes
نویسندگان
چکیده
منابع مشابه
Adaptive diversification of bitter taste receptor genes in Mammalian evolution.
The diversity and evolution of bitter taste perception in mammals is not well understood. Recent discoveries of bitter taste receptor (T2R) genes provide an opportunity for a genetic approach to this question. We here report the identification of 10 and 30 putative T2R genes from the draft human and mouse genome sequences, respectively, in addition to the 23 and 6 previously known T2R genes fro...
متن کاملVariation in the human TAS1R taste receptor genes.
We have performed a comprehensive evaluation of single-nucleotide polymorphisms (SNPs) and haplotypes in the human TAS1R gene family, which encodes receptors for sweet and umami tastes. Complete DNA sequences of TAS1R1-, TAS1R2-, and TAS1R3-coding regions, obtained from 88 individuals of African, Asian, European, and Native American origin, revealed substantial coding and noncoding diversity: p...
متن کاملA Matter of Taste: Lineage-Specific Loss of Function of Taste Receptor Genes in Vertebrates
Vertebrates can perceive at least five different taste qualities, each of which is thought to have a specific role in the evolution of different species. The avoidance of potentially poisonous foods, which are generally bitter or sour tasting, and the search for more nutritious ones, those with high-fat and high-sugar content, are two of the most well-known examples. The study of taste genes en...
متن کاملTaste receptor cells responding with action potentials to taste stimuli and their molecular expression of taste related genes.
Recent molecular biological studies have revealed many molecular aspects of taste transduction in receptor cells for each taste categories which are referred to as salty, sweet, sour, bitter and umami in human respectively. (Lindemann, 2001; Gilbertson and Boughter, 2003). For example, ion channels such as ENaC, ASIC and HCN mediate salty and sour taste and G-protein-coupled receptors such as T...
متن کاملDrosophila sweet taste receptor *
Like the Sac locus controlling sugar sensitivity in mice, the taste gene Tre of the fruitfly Drosophila was discovered in wild populations as a genetic dimorphism controlling gustatory sensitivity to a sugar trehalose. By activating a P-element transposon near the gene locus we obtained induced Tre mutations and analyzed the associated changes in gene organizations and the mRNA expressions. The...
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ژورنال
عنوان ژورنال: Annual Review of Nutrition
سال: 2007
ISSN: 0199-9885,1545-4312
DOI: 10.1146/annurev.nutr.26.061505.111329